Respecting your last wishes | Stone King Blog

Who would decide whether you should receive life-saving medical treatment if you were unable to? When someone becomes mentally incapacitated it?s often left to family and doctors to make difficult decisions about their medical treatment.

A living will enables you to record your wishes regarding your future medical treatment in case you become incapable of doing so. Strictly speaking, a living will is not a proper legal term but is commonly used to describe documents called advance decisions.

An advance decision allows you to make a decision to refuse life-sustaining treatment while you are still mentally competent which will take effect when you are not. Of course you don?t have to wait until you are diagnosed with an illness before making a living will. But an advance decision to refuse life-sustaining treatment must be in writing ? signed, dated and witnessed. It will then be legally binding.

Your wishes can become invalid, however, if you do something that is inconsistent with your decision to refuse life-saving care. Similarly, an advance decision may no longer be applicable if, for example, there have been medical advances which had not been anticipated at the time of writing the document.

That?s why it?s a good idea to regularly review your living will to avoid any uncertainty and make sure you discuss your decision with your doctor, family and friends. Stone King?s trusts and estates team can help you write a document that is both legally binding and applicable.

For more information about living wills please contact Kathryn Layzell on 01225 324461.

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Source: http://www.stoneking.co.uk/blog/?p=137

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More Early iPhone and iPad Prototype Designs Surface in Samsung Trial Documents

Last week, we noted that documents filed as part of the ongoing lawsuit between Apple and Samsung had revealed a few images of early iPhone prototype designs, including some that revealed similar design to what ultimately appeared years later as the iPhone 4/4S.

AllThingsD has now put together a gallery of dozens of images from the court documents showing even more of Apple's ideas for the iPhone and iPad.

Among the many filings on Saturday was a document with dozens of sketches and prototypes for both the iPhone and iPad. Some had already been included in earlier filings, but Saturday?s collection was particularly extensive.

The filing features a host of sketches, images from computer-aided design programs, and photographs of actual models that Apple fabricated as part of its design process.

Among the concepts that had previously surfaced was a series from Apple's Shin Nishibori, whose early Sony-inspired designs were immediately leapt upon by Samsung as evidence that Apple had copied the iPhone design from earlier innovators. But as noted by The Verge, additional prototypes dating even further back show that Apple had the iPhone aesthetic well in hand even before the Sony-inspired designs were created as a side project.

"Purple" dates back to August 2005 ? months before the Jony prototype was originally designed. According to the documents, Shin Nishibori's Sony-style touches were simply "an 'enjoyable' side project," embellishments on a concept Apple had already designed. The documents contend that Purple remained free of the alleged Sony inspirations, ultimately giving birth to the iPhone in 2006 (and looking decidedly like the iPhone 4).

AllThingsD is keeping a close eye on all of the trial developments, with Ina Fried tweeting from the courthouse today to provide updates on important developments in the high-profile case.

Source: http://www.macrumors.com/2012/07/30/more-early-iphone-and-ipad-prototype-designs-surface-in-samsung-trial-documents/

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Jada Pinkett Smith Tweets Bikini Pic, Words of Encouragement

Jada Pinkett Smith has no problem showing some serious skin when it comes to important causes.

The actress got naked last month in the name of human trafficking awareness, and now she's showing off her bikini body for the sake of the over-40 crowd.

Smith Tweeted a photo of herself in the water over the weekend, along with the caption: "To my Forty and over crew! Don't believe the hype…we DO get better with age!" 

Of course, it helps when you are rich and can afford a personal trainer and a personal chef and can take the time in between movies or TV shows to work out like crazy. But still.

Jada has been battling divorce rumors in the press for months now, but there are no actual signs that she and Will Smith will be splitting any time soon.

Source: http://www.thehollywoodgossip.com/2012/07/jada-pinkett-smith-tweets-bikini-pic-words-of-encouragement/

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Source: http://www.indianhomedesign.com/2012/07/1621-sq-ft-simple-house-elevation-from.html

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ReDigi takes out loans as EMI legal battle continues | Daily Serps

As controversial MP3 resale service ReDigi continues to battle a lawsuit launched by EMI, Digital Music News has noted that the tech start up has recently secured an extra $760,000 in funding.

However, the money has come from loans rather than equity-based investment, meaning it will have to paid back with interest down the line. Presumably that means that the company needs new monies to develop its product while paying ongoing legal fees relating to the EMI case, but that, given the uncertainty the litigation creates, few investors would be willing to put money into the firm in the traditional way.

As previously reported, the legalities of a website that enables people to resell used MP3s are somewhat ambiguous, which prevented EMI from securing a summary judgement in its favour, but which could make any full court hearing time-consuming and expensive. ReDigi insists its service complies with US copyright law, mainly by relying on the so called ?first sale doctrine?, while EMI argues that ReDigi just helps others to commit copyright infringement.

While ReDigi won round one of the legal battle ? when EMI failed to get its summary judgement ? at the time various commentators wondered whether the start-up had the funds available to fight such a complicated lawsuit, even if ultimately the courts ruled in its favour. such speculation grew when the firm?s lawyer quit the case, implying some bills remained unpaid. But the tech firm insisted it could see the case to its conclusion, adding that it had switched lawyers to bring in representatives particularly experienced in this area of law.

The new loans will help with that plan presumably, though whether it will be enough to allow ReDigi to weather this storm and grow its business remains to be seen.

Sections: Digital ? In the Pop Courts ? Music Business | Tags: EMI, ReDigi

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ReDigi takes out loans as EMI legal battle continues

Source: http://dailyserps.com/redigi-takes-out-loans-as-emi-legal-battle-continues/

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Laclede Group profit, sales decline from 2011

ST. LOUIS (AP) ? The Laclede Group Inc., owner of Laclede Gas Co., said Friday that fiscal third-quarter revenue dropped sharply and profit fell 45 percent compared to last year, when asset sales boosted earnings.

Excluding that 2011 gain, the company said adjusted earnings rose 5 percent over last year.

Revenue plunged to $186.8 million from $344.3 million, which the company blamed partly on mild weather that hurt results at its gas-distribution utility.

Net income was $8.4 million, 38 cents per share, but would have been 40 cents per share excluding losses from derivatives, the company said. That was down from income of $15.4 million, or 69 cents per share, a year earlier, when the sale of excess propane inventories added $6.1 million or 27 cents per share to earnings.

Laclede Group, based in St. Louis, has about 625,000 residential and business customers in that area.

In afternoon trading, Laclede Group shares rose 57 cents at $41.36.

Source: http://news.yahoo.com/laclede-group-profit-sales-decline-2011-194115733--finance.html

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Government on track with federal health exchanges: official

WASHINGTON (Reuters) - The Obama administration on Friday said it is on track to set up federal health insurance exchanges by 2014 in U.S. states that fail to establish their own regulated insurance markets under the U.S. healthcare reform law.

The Health and Human Services Department is also preparing to issue new guidance for states before the end of the summer on how federally facilitated exchanges are expected to operate, a senior official said.

"We realize that not all states will be ready to establish these exchanges by 2014, so we are on track to set up the federally facilitated exchange in those states. It is on track to go live," said Mike Hash, the senior official overseeing the administration's health exchange effort at HHS.

His remarks come at a time of mounting tension between the administration and some states over the exchanges and other provisions of President Barack Obama's healthcare reforms.

The reform law known as the Patient Protection and Affordable Care Act calls on states to create regulated exchanges where an estimated 16 million uninsured Americans are expected to qualify for private health coverage at rates subsidized according to income via federal tax credits.

Tax credits would be available for a family of four earning up to $88,000 a year.

The Affordable Care Act survived a major legal test a month ago when the U.S. Supreme Court upheld the law as constitutional but allowed states to opt out of an expansion of the Medicaid program for the poor.

But the reform provision on exchanges has since become an election year flashpoint for several Republican governors who reject the plan, along with the Medicaid expansion, as too costly and bureaucratic.

Officials in still more states are waiting to see who wins the November election before taking action.

Republicans, led by their party's presumptive presidential nominee, Mitt Romney, are vowing to repeal "Obamacare" if they win big in November's general election.

State resistance to the exchanges, spearheaded by the governors of Florida, South Carolina, Louisiana, Mississippi and Texas, has been largely overshadowed up to now by the concurrent fight over Medicaid, which would extend coverage to an estimated 11 million people who are now uninsured.

MISSING THE BOAT?

Speaking at a Capitol Hill conference on health reform, Hash said the administration wants as many states as possible to set up their own exchanges but has begun testing a federal exchange model that can be rolled out "in any number of states."

HHS is scheduled to host a series of meetings across the country to discuss reform issues with state representatives and others. It has scheduled forums in the District of Columbia, Atlanta, Chicago and Denver from August 14-22.

Thirty-five states have accepted a total of $850 million in federal grants to plan and establish state exchanges. But only 13 and the District of Columbia have declared their intention to establish their own marketplaces.

According to the Commonwealth Fund, a private foundation that promotes healthcare system improvements, 24 states have taken no action toward establishing an exchange while eight others have declared that they will not pursue one.

The administration has set a November 16 deadline for states to say whether they intend to set up their own exchange, create one in partnership with the federal government or let federal officials establish one for their residents.

Initial enrollment is due to begin nationwide in October 2013, three months before the Affordable Care Act's provisions come into full force on Jan 1, 2014.

The National Association of Insurance Commissioners, which represents insurance regulators in all 50 states, says state governments that opt for federal exchanges risk losing control of lucrative private health insurance markets within their borders.

"If the states do not get ready for this, then they lose the ability to regulate. It's the whole marketplace," Brian Webb, NAIC's health policy and legislation manager, told the forum hosted by the nonpartisan Alliance for Health Reform.

"They may get their wish and not be able to do anything in their marketplaces," he said. "There's not an insurance commissioner in the country who wants to say, 'No, we're not going to regulate that.'"

Tim Jost, a health law expert at Washington and Lee University, warned the same audience that inactive states may already have "missed the boat" for establishing their own exchanges on schedule.

The job involves myriad tasks ranging from establishing eligibility guidelines for consumers to establishing information technology systems and certifying qualified insurance plans.

"If you work backwards from October (2013), you get almost to the present," said Jost, who believes most states will wind up with federal exchanges in 2014 then transition to their own operations over time.

(Editing by Andrew Hay and Eric Walsh)

Source: http://news.yahoo.com/government-track-federal-health-exchanges-official-175945701.html

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Tips On Having A Lusher Lawn | Arty Apt

Do not assume you?re stuck with a boring, dead landscape in the winter. Look for ways to add splashes of color to your lawn. Brightly colored furniture, berry-producing woody shrubs, evergreens, and attractive hard scape designs, like pathways, can all keep your yard interesting when everything else is grey and brown.

Container planting works great in any garden. Container plants are easy to move around if you have plants that need different levels of light than what is present in your yard. They are also raised from the ground, making them easier to tend to. Place a few in your yard to add visual appeal.

When landscaping, you must know the difference between perennials and annuals, as well as what flowers, plants, and shrubs work best, in particular, geographical areas and under certain climates. You must also remember your seasons when landscaping as well. It is very important that you know this information in order to get the best results from your landscaping experience.

In today?s economy, there are not a lot of us who can afford to landscape their entire yard all at one time. One economical way to a beautifully landscaped property is to divide your landscaping project into phases. By doing the project in stages, you will not have to take out a loan or use your credit cards to up-grade your lawn. With dividing the project in phases,you can also purchase perennial plants late in the growing season, when the cost is lower.

Divide your landscaping project into phases. Most people don?t have the resources to buy everything they will need at once, doing so can often leave you disorganized. Instead, split your project up into sections, that you can tackle one at a time for a cheaper more organized way to do your own landscaping.

Speak often with your neighbors and friends about your landscaping plans. They may also want to do work on their yards, and you may be able to go in together to rent things like chippers or tillers. By sharing this equipment, you will all save money and be able to get your work done.

At nighttime, if you want to show off your lawn, plants, and other aspects of your outdoor area, you may want to invest in landscape lighting. These lights can be placed above your walkway, your lawn, or sidewalk and they can be purchased at many home improvement stores in your area.

If you plan on staying put, buy smaller plants instead of larger plants. This helps you save money on your landscaping costs. You will have to wait a few seasons for the plants to come to full size, but it is worth saving the extra money if you are sticking around.

Bring the inside out when enhancing your home?s landscaping. Look at the accent pieces that you have around the inside of your home and consider using similar items that are weather resistant for the outdoors as well. It is fun to had a little whimsy with wheelbarrows, benches, or various statues.

Emphasize perennials in your landscaping plan to have year round coverage. Perennials save the landscaper both money, and labor because once they are in place, all they require is basic maintenance. Annuals of course, have their place in landscaping, as well but over the long run they are more costly and labor intensive than perennials.

Seek out inspiration not just from landscaping magazines, and books, but also from your local neighborhood. Seeing what your neighbors are growing successfully can help steer you towards plants that are appropriate for your area. If you find a garden you truly admire, ask the homeowner, if they have any advice they can share with you.

Use paint to your advantage when designing your landscape. From patio furniture to statues, fountains, birdhouses and even painted rocks, a fresh coat of paint in a bright shade can really brighten up individual elements in your yard. Coordinate paint colors with your favorite blossoms for a cohesive look that pops.

If you are installing lighting it is a good idea to make sure that you do not overdo it. While it is nice for walkways to be well lit, you do not want to make your yard look like everything is under a spotlight. Furthermore, make sure that it is evenly lit since having bright areas and then dark areas near one another does not look good.

Plan your landscape well. The best landscaping projects begin with proper planning. To properly plan a landscaping project begin by drawing the dimensions of the area to be landscaped to scale using graph paper. This diagram will include plotting the locations of any structures in the area including established plants, water features and walkways.

Your dreams can come true, if you use what you?ve read here and start working on your yard today. The most simple of idea can have a huge impact, so start small and build up as you go. Every minute you put into it will show in the final result, so dedicate yourself to change and you?ll be pleasantly surprised in the end.

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Source: http://artyapt.com/blog/tips-on-having-a-lusher-lawn/

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Credit Debt Relief Programs ? Debt Relief Mag

Anyone can feel miserable in life when they have to face debt related issues. The only way to better your life in such situations is by repaying your debts. Debt repayment options can be easily found these days and a person can choose the right debt repayment option in order to eliminate his debts. Choosing the right debt repayment option also helps to ensure that you do not have to declare bankruptcy in order to get rid of your debts. Keep in mind that there is plenty of debt management plans that can help you get rid of your debts in an easily manageable manner. However, you must choose the right debt management plan in order to do so because not all debt management plans are right for you. Mostly people choose a debt management plan that worked for someone they knew. Keep in mind that the debt issues you are facing and the debt issues someone else is facing can be entirely different. Therefore, a person must never choose a debt management plan after seeing it working for someone else. It is best that you chose a reliable debt management company so that they can suggest you a good debt management plan to help you get rid of your debts. If you want to choose a debt management plan on your own, then first, you must consider your own financial situation. For this, you will need to sort out all of your financial information. Make a detailed list of all of your debts, interest rate on your debts, your creditors, and any other information related to your debts because this information will be needed in order to determine your current financial situation. Considering your financial situation is essential because without this, no company or not even yourself can choose the right debt management plan for yourself. Therefore, make sure that you are not omitting any details that can determine your current financial situation. When you have carefully sorted out your financial situation, you need to find a reliable source to get debt advice. Paid companies are one reliable option, but not everyone can afford to pay a company to get advice or to get a debt management plan. Therefore, the only option most people are left with are the charitable organizations that work free of cost. Charitable organizations are easy to find these days because most of these organizations have good reputation and may be you know some of them. However, if you do not know any reliable organizations that provide free of cost debt advice and debt management plans then you should ask someone who might know. Keep in mind that you must share your updated information with the company you are choosing to get debt help from, whether it is in the form of debt advice or a debt management plan. If you do not share your correct information with the company, then there is no assurance that the company will be able to provide you with a debt management plan that can work for you. Author bio: Muhammad Azam is an avid blogger and financial advisor. He has experience in debt relief industry. If you are looking for reliable information about iva, debt management plans and other debt relief options then read his blogs. Source: aguileon.com Source: debtreliefmag.com Source: debtsettlementusaco.com
Source: debtsettlementusaco.com

Video: Wisconsin Bankruptcy Blog (1/16) What is bankruptcy?

Debt Settlement Myth #6: It?s Safe To Take 36

Here at ZipDebt, our clients settle most of their debts before charge-off, and the remaining accounts are usually resolved within a total program duration of 12 months. Why are we so much more successful at expediting this process vs. the folks quoting 36 month programs? Simple. We are not focused on ?making the sale? by presenting an option that is simply not effective on the long run. We prefer to push our clients to ?go find the money? to settle quickly, and that is precisely what most of them do once they understand how the math works! We get our clients to start thinking in terms of the ASSETS they still have left to work with, and converting those assets to cash, instead of relying exclusively on the client?s monthly budget the way most companies do. We aim for fast relief instead of slow torture!
Source: getoutofdebt.org

Debt Relief Concerns for Families and Couples

While I was in collections, I had the opportunity to analyze the debt settlement industry. I was open-minded at first, but as I learned more and saw how unreliable the traditional debt settlement approach was, it motivated me to start my own debt relief company, back in 2002, and offer debt settlement in a successfully reliable way. What I learned from my time in collections, was if a consumer could settle their debts quickly, debt settlement was a reliable option.
Source: avoidbk.com

Debt Reduction Programs That Will Help During This Tough Economy

Yet another choice that is utilized frequently and is a much better method to take than a loan is a consumer credit counseling program.? These types of packages present consumers decreased rates of interest and combine the monthly obligations into only one payment.? In many cases this sort of a plan will assist the consumer to realize personal debt liberty inside of 4-5 years.? There are still drawbacks using this program, it will negatively have an affect on ones credit rating, and these programs can be extremely tough to carry out.? The explanation for this is because if the customer misses a payment they will be kicked off the program by the creditors themselves and as a consequence lose the main advantages of low interest and one payment per month.?? This program genuinely matches someone that is not struggling to maintain their minimums but would just like to get free from personal debt a lot quicker.
Source: tradingreviewsblog.info

albertfelds: Get Tax Debt Relief and start Experiencing Your life

debt relief. You could possibly need the help of a CPA (Certified Manifeste Accountant), Enrolled Agent (EA), and/or tax accountant/attorney. With several choices readily available, you need to assessment what exactly is presented to help make a proper decision. Delay or procrastination is expensive. As a substitute of piling up your debts, look at consulting a support provider to help you untangled effortlessly your after challenging tax debt problems. Get help with establishing a reimbursement approach streamlined only for you; this may be performed by a professional with out complication. Along with the support of a CPA or EA, you can simply comprehend the entire course of action. Tax debt relief professionals make methods trouble cost-free; you just deliver all of the facts and information for the accountant and they?re going to do the remainder. Tax relief companies offer numerous services that may assist you to to incorporate; Gives you in compromise Aid with filing unfiled tax returns IRS audits and notices Tax penalties Launch from IRS levy Declaring non collectible status Some key notes regarding non collectible status are; To become thought to be for this status, a taxpayer or his representative have to convince the IRS that he/she simply cannot meet up with the tax stress. The debt is not really be forgiven, it is simply delayed and all fines and penalties will probably be put on maintain. If the taxpayer stays within a non collectable status for 10 a long time, the statute of limitations kicks in along with the IRS will create the debt off; on the flip side, when the taxpayer regains greater economical footing, the IRS will resume collections action to collect the debt. Fortunately tax debt relief pros usually are not hard to find, commit slightly time doing all of your exploration on the net and placing some telephone calls. Setup some appointments with those tax pros that appear finest certified to deal with your state of affairs. No matter whether you?ll need assist to halt IRS levy, or filing back again taxes or have the proper assist and satisfaction. Costen Tax Team gives you IRS tax resolution services and tax debt relief services to tiny businesses and folks. Because 1999, we now have assisted countless taxpayers deal with their IRS and state issues. We are trained professionals who will cope with your scenario with honesty and integrity. We are Enrolled Brokers (EA). EAs are classified as the only federally accredited tax practitioners who specialise in taxation in addition to have unrestricted rights to symbolize taxpayers ahead of the IRS.
Source: blogspot.com

foundational soviet: Student Loan Debt Relief

Perhaps one of the best ways to get student loan debt relief when you are struggling with a huge debt is to get in touch with your bank. Banking institutions might generally provide a forbearance or deferment during a single phone call. Banks might offer individuals deferment when they are in situations such as unemployment, underemployed, family issues like child birth, becoming disabled or entering public service. Deferments generally last for 6 months and the debtor is not forced to make any kind of payments during this period. This deferment could be an easy way to get up to date with payments without worrying about the financial debt for several months.
Source: blogspot.com

Huanya policy: the United States refers to the steady short

technical side, the United States refers to the strong European midday Monday pulled up to a maximum touch the 84.00 mark, but then suppress by short-term resistance, the United States refers to a mild fall, the bottom on Monday, Asia City, low steady 83.61 , Monday to close at the upper shadow candle. 4 hours chart, the United States continue to maintain the shock upward trend, moving average system to maintain a long array, the top breakthrough 84.00, above the pressure of the disk is mainly located 85.00 integer bit and 20 071 high of 85.40 near, if the United States that continue to rise, The medium-term pressure will be located in the 2005 high point of 92.63 and 2009 high of 89.62 consisting of the downward trend line. Below support will mainly consider the day 50 MA, the United States since mid-six so far repeatedly held steady in the moving average. Short-term expected days of America refers to the breakthrough to 84.00 after the top of the pressure is 84.39, if still limited by 84.00 resistance and below support to continue to consider the Monday low of 83.61 and upward gap at the bottom of 83.49. Focus on the following
Source: forex-news.co

Judgments Often Disrupt Debt Settlement Plans ? Debt Relief Mag

We will try to highlight the advantages and disadvantages of IVAs here. An IVA is a legal agreement between you and your creditors. So long as you meet IVA criteria it allows you to repay what you can afford each month, usually over a five year period. At the end of the IVA term, assuming you have completed the arrangement as agreed, the remainder of your unsecured debt within the IVA will be legally written off and you will be free of debt. Monthly contributions to the IVA will be based what you can afford after other essential costs such as mortgage, utility bills and food etc. have been taken into consideration. There are of course advantages and disadvantages to IVAs which makes seeking advice on an appropriate debt solution worthwhile. One particular advantage is affordable, reduced repayments. Payments are fixed at the start of the arrangement to give peace of mind that you can afford to continue with the proposal for the agreed term, usually five years. Indeed the fixed term is also attractive as individuals can see an end to their debt problems. This is in comparison to less regulated debt management plans which, in many cases, have no fixed term or end date. Entering into an IVA takes away creditors rights to take legal action to enforce repayment of the debt so long as payments are upheld throughout the term of the proposal. It also stops penalties such as interest charges being applied. However, as with most things there are also a number of disadvantages to an IVA and these must be highlighted to individuals so they are entering into an agreement armed with all required knowledge. An IVA is a particularly good debt solution for some but may well not be for others. IVAs deal with unsecured debts such as loans and credit cards but not secured debts such as mortgages. Mortgages and other secured debts must be funded outside of the arrangement and usual stipulations still apply to the mortgage where failure to make regular payments on time can lead to your home being repossessed. However, if you are struggling or indeed missing payments at this stage, an IVA can allow funds to be concentrated on these essential commitments. One of the main restrictions when entering an IVA will be the ability to borrow more whilst the IVA is in progress. Further debt is not allowed without the permission of the Supervisor (Insolvency Practitioner) of your IVA. Additionally, a property you own may need to be revalued towards the end of the IVA with any realisable equity possibly having to be brought into the arrangement. In many cases however, this equity may not be realisable if the amount of equity is relatively small or costs are prohibitive. It is possible where equity cannot be realised, that the term of the IVA is extended a further 12 months. An IVA is a method of insolvency, and will impact on your credit rating. However, the fact you are considering an IVA in the first place means it is highly likely that your credit rating is already in need of repair. A record of your IVA will remain on your credit history for six years after it begins. This means that you will have a clean credit history a year after your IVA has finished (assuming it`s a five year IVA). For professional, debt solutions advice, contact us today we offer personal services to suit the needs of each of our clients. As well as detailed IVA advice, we also offer general free advice on debt. Source: abcarticledirectory.com Source: debtsettlementusaco.com Source: typepad.com Source: debtreliefmag.com
Source: posterous.com

Tips on Getting Red Deer Credit Counseling or Canadian Bankruptcy Help

If you have debts that are too large to manage with the income you make ? regardless of the reason ? you may already need the expertise of a licensed bankruptcy trustee. This federally-trained, supervised, and certified debt relief professional can give you Canadian bankruptcy help, assist you in applying for a consumer proposal for long-term debt relief, or give you access to options that generate legal and long-term debt relief. A trustee will provide you with a free consultation to review your finances and are well versed in all forms of debt remedy. If after a thorough review of your situation it?s determined that credit counseling is advised, your trustee can put you in touch with the right counselor.
Source: personalbankruptcyreddeer.com

Related posts:

1. Find out about all of your best credit card debt relief programs
2. Credit Management Programs
3. Credit Debt Relief Programs
4. Government Credit Card Debt Relief Programs? Are They Real?
5. Credit Card Debt Relief Programs

Tags: Debt, debt management company, debt management plan, debt management plans, IRS

Source: http://debtreliefmag.com/credit-debt-relief-programs-3/

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Wondolowski nears scoring record

Thierry Henry, David Beckham, Landon Donovan have the names that will dominate conversation tonight from Major League Soccer?s side as the All-Stars do their thing against European champion Chelsea. (Coverage begins at 8:30 p.m. on ESPN2)

Chris Wondolowski? He?s one of the All-Stars of lesser brilliance in the greater cultural stratosphere. Soccer fans know all about the San Jose Earthquakes prolific scorer, but the general public may stare past the man known as ?Wonder Wondo? as they tune in tonight.

It takes an extended run with the national team or a move overseas to a fancy, name brand league to jump the divide in Q Score.

Or, perhaps it could happen for a man who sets the long-standing single season scoring record; Wondolowski may just be the fellow to do it.

He stands on 17 goals, easily best in MLS. His Earthquakes have 12 games remaining. Wondolowski?s current rate of scoring (just less than a goal a game) puts him squarely into the Roy Lassiter territory.

(MORE on MLS All-Star game: Format needs tweaking)

Lassiter hit 27 goals for the Tampa Bay Mutiny in the league?s debut season, 1996. (A very different league, by the way, with nothing close to the quality seen now.) So, on the back side of tonight?s All-Star activities at PPL Park, expect to hear about the chase weekly.

Wondolowski has a fantastic team around him, a confident unit capable of winning in a variety of styles. That?s going to help. I asked him yesterday if it would take a big game, a hat trick hit, perhaps, in order to make a big push for the mark?

?I don?t score that many hat tricks,? he said with a laugh. ?I?m just hoping for a brace [two goals] here and there.?

How the single-season scoring list looks today:

Source: http://prosoccertalk.nbcsports.com/2012/07/25/81537/related/

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Light-activated brain cells boost monkey skills

Treating disease by stimulating brain cells with light is a step closer to reality following the first demonstration that the technique can improve mental performance in monkeys. Two monkeys performed better on simple computer tasks after light was used to boost the activity of brain cells necessary for the task.

"For the first time, we were able to change behaviour in primates with our technique," says Wim Vanduffel of Massachusetts General Hospital in Charlestown, who is head of the group that performed the experiment.

Known as optogenetics, the method has the potential to treat conditions such as epilepsy, where the light could temporarily deactivate the brain cells that cause seizures, or Parkinson's disease, where it can activate cells that make dopamine, the neurotransmitter vital for controlling mobility that those with Parkinson's lack.

Previously, it has been used in nematode worms to trigger them to lay eggs, and mice to relieve depression and paralysis. Researchers have also used it in monkeys, but only on single, isolated neurons. Vanduffel and his colleagues wanted to see if they could extend this to entire networks of cells, boosting a monkey's ability to perform a simple computer-based task.

Natural performance enhancers

First, Vanduffel's team scanned the two monkeys' brains using functional magnetic resonance imaging while they followed a green dot on a computer screen. From the scans, the researchers could tell that the monkeys relied on an area of the brain called the arcuate sulcus to do the task.

Next, the team inserted a gene that reacts to light into the cells of the arcuate sulcus. Originally from algae, the gene makes a protein called channelrhodopsin-2, which reacts to blue light by admitting ions into the brain cells, activating them in the process. They gene was ferried into the cells using a virus.

Finally, the team guided fine, light-conducting needles into the same area through a port permanently attached to the animal's skull. The monkeys then repeated the task as the researchers pumped light into their brains.

Comparisons of the monkeys' performances before and after the treatment showed that they reacted about 10 per cent faster when undergoing light stimulation. "One monkey reacted about 20 to 28 milliseconds faster, and the other about 15 milliseconds faster," says Vanduffel.

Vanduffel says that in unpublished experiments, monkeys undergoing the technique while carrying out a more complex task improved even further. "My hunch is that the harder the task, the more significant the effect," he says.

Proof of principle

"This is just proof of principle, and there's a very, very long way to go before we can start using it in humans," he adds.

Although treating humans is a distant prospect for now, Vanduffel says the method is evolving fast. Gene switches have been identified that work in very specific brain areas, potentially enabling light to target unhealthy cells without disrupting healthy ones.

"This work is exciting because they've shown that pre-stimulating an area of the brain necessary for the task makes processing faster," says Arnd Pralle of the State University of New York at Buffalo, who uses magnetism instead of light to activate brain cells in worms.

Another important advance, says Pralle, is that whole networks of cells were activated for the first time, compared with single or small groups of neurons stimulated in previous monkey and rodent experiments.

Journal reference: Current Biology, DOI: 10.1016/j.cub.2012.07.023.

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Outdated Job-Search Techniques to Avoid!! | Career Point Jobs ...

By Dorcas Karuana,
There are certain things you can do to improve your chances of getting an interview, and other things that may hinder your job search. Here are some job-search techniques that you should try to avoid if you want to improve your chances of getting hired.
1. Submit to new job postings that are already old
Many jobs that get published have already been circulating for a while. Employees within the company will be asked if they know anyone who's good for the position. Headhunters will be contacted. Word-of-mouth spreads the job. By the time you see the job in the classifieds and apply, candidates from far and wide have sent in their resumes, and you're already at a disadvantage. The job may simply be posted so that the company can be seen to be offering equal opportunities to everyone. So if you really want a job in a certain field or company, be proactive. Get to know the hiring managers or HR people. Do some cold calling. Ask around. You want to be fishing for the best jobs before they're announced to the masses.

2. Send out masses of unsolicited resumes
This was a tactic a friend of mine employed as we were finishing college, and it did not work. The mass-mailing is usually fruitless and can waste a great deal of your time and money. It may also irritate hiring managers and these resumes usually end up in the trash.

3. Assume that if there's no job posted, it means there?s no job available
A lady friend of mine applied for a sales job through a recruitment company. She did well in initial interview and was shortlisted for the final interview. The position she applied for was sales while in the interview a member from the recruitment company on the interview panel realized that she had a good education in Human Resource. She was given a job in the recruitment company.
The moral of this story, whether it's true or "inspired," is that opportunities present themselves everywhere. You can't assume that the only jobs around are the ones that are advertised. Your skills could be perfect for a company and they may not even know they need you yet. Keep your eyes and ears open, be inventive and be proactive. You never know where it may lead you.

4. Apply for more jobs to increase your odds
Here's another common error. "If I apply for 100 jobs, I'll get more interviews and that will mean more chances of getting hired." Well, not really. If you're sending standard cover letters and CVs to every job that sounds remotely interesting, you'll fail to get noticed by any of the hiring managers. You're basically hoping that your CV gets picked from an enormous pile and you get the call. You need to be smarter; be targeted. Pick out the jobs you really want and write cover letters and resumes that are tailor-made for those jobs. Do your homework. Find out everything you can about the industry, company and role then make an application that cannot be ignored. Now, you're not relying on chance any more. In this day and age, quality is far better than quantity.

5. Have only one resume and cover letter
This is related to the previous tip. Competition for an opening is very high. So do not ever rely on one standard CV and cover letter for every job you apply for. Job searching is hard work; some say it's a full-time job, so you cannot just make 20 copies of both your cover letter and CV application and apply for 20 different job postings.? Worse still, if you do apply online or via email, a simple copy and paste may not be good enough. Focus. Find out how the company operates, what is required for that job and the challenges they face. Present yourself as a solution to the companies need. It proves you're a step ahead and do nothing by halves.

6. Rely on just one job search technique
It's great to check a site like JobsKenya.com every day. But don't pop online, see what's new, and then log off. It's outdated thinking to expect the ideal job will be in the one place you're looking. This is the age of digital networking, featuring FaceBook, LinkedIn, Twitter, Google + , and so much more. Dive into them all. The perfect job could be lurking inside any one of them.

7. Focus on yourself
What? But it's all about you, right? Not exactly it's all about the employer. They're like a first date and they want to know how interested you are in them, not yourself. It may have worked well in the past, but that kind of "me, me, me" attitude does not sit well with employers these days. Let them know how you fit in with their organization. Show them why you would make a great addition to their team. Set your sights on making the employer feel like they're the only company you'd ever want to work for, because they're the perfect fit. When you focus on them, they focus on you.

8. Refuse to change careers
Remember the days when people were accountants at one company for 30 years and then got a golden handshake at a retirement? Those days are gone. Nowadays, there is rapid and constant changes in technology as well as new careers are springing up all the time. There was a lady who was a secretary for over 20 years, because of the importance of her role which required a great deal of work to be handled manually, the demand for secretaries was great and their salary was also good. With the introduction of IT in the office and use of networked phones employees are now more independent. Unfortunately, the lady was on a salary that was close to Ksh 100,000 a month. Her skills and role were obsolete. With some retraining however, such as business administration, human resource or accounting she could make herself relevant. How many jobs are out there now that weren't around 10 years ago? Or even 5? For instance, social media is now booming. It employs many people. They had to come from somewhere and no doubt they switched career paths. While you shouldn't cast your net so wide, as to be fruitless, consider fields that are related to yours in some way.

Dorcas is a Recruitment Officer. Corporate Staffing Services. email: dorcas@corporatestaffing.co.ke. Web address. www.corporatestaffing.co.ke???

Register your CV with Us For Free.?

Source: http://www.careerpointkenya.com/2012/07/job-search-in-kenya.html

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Baby's (Mine) 1st Birthday Pictures | Babys First Year Blog

So you know that beach party I was raving about? All of those amazing ideas I had curated and was dead set on executing?

Yea.

Didn?t happen.

What did happen was a?most lovely, sweet affair, in our backyard with?most of our nearest and dearest. I?l be the first of any to proclaim the?many virtues of all that is DIY.?Especially?when it comes to anything baby, toddler, house and home related. And obviously food/drink recipes. (Hello Pinterest,?my sexy BFF).

As we?momma?s know, life in the land of baby and toddler takes on a carnivalesque hue at times. Wherein we just don?t have the time to put?Martha Stewart to shame. Which is fine, because our babies?

They. Don?t. Care.

You could stick a candle in a?McCain cake, let them roll around naked and have those who love and dote upon them the?most show up. That right there is all they need and/or know about a party in their honour being awesome. Oh, and the presents. But that bit doesn?t come until later.

I guess what I?m trying to say, is all of these grand birthday parties are really for us. The adults. And the expectation of presents, well ? that all up to us to. These little humans after all, are essentially?moulded by us. So, what?may be cute when they are younger? (Ripping open a mountain of pressies). Will be far less so when they start to demand or expect it, often skulking when they don?t get it. We?ve all heard the term, ??I?ve created a?monster?.

?Nuff said.

It should also be?mentioned that technically, Abby doesn?t turn 1 until this Thursday ? we had her grand hoopla of a party earlier to accommodate guest RSVP?s. So you?can expect to be hit with another round of epic cuteness come the actual day of her birth. Until then though,?may your ovaries (or other baby-loving parts) be tickled by these?

• 

  The Diva

  Looking every little bit the darling, sweet, saucy little monkey that she is.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#the-diva

• 

  The Diva's #1 Hero

  Her brother, who is equally sweet and saucy. (Also? Tubes rule. Rule I tell you).

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#the-divas-1-hero

• 

  Water Play

  While we didn't make it to the beach, we still had lots of water activities going on. Kiddie pool , sprinkler, water balloons (for the older kiddos) and sponges. Happy Days.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#water-play

• 

  Everting In The Mouth

  All the time, everyday, like gangbusters.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#everting-in-the-mouth

• 

  Show & Tell

  As of late she is pointing at everything, (and I mean everything, all of the everything, everywhere, it is fascinating you know). If the object of her desire is safe enough for her to fiddle with and inevitably shove in her mouth, we give it to her. Wherein she promptly lifts it up high, often shoving it up ones nose, proclaiming, 'THIS!!' Oh, the sweet victory.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#show-tell

• 

  The Magnificence!

  Pure, unadulterated joy. (This expression also says, 'lookit meeee! LOMG, seriously though, lookit meeeee!)

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#the-magnificence

• 

  Non-Stop Good Times Over Here

  She has a slight asphyxiation with opening her mouth wide, leaving it gaping, with tounge lolling at times. She's been doing it constantly. While dancing, while crawling, when she wakes up and boogies in her crib...watching herself in her closet mirrors - quite entertained by the whole show. Put on by herself. That's my girl.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#non-stop-good-times-over-here

• 

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#see

• 

  For Full Effect

  In case I wasn't clear enough before. It would appear as though this little girl was having herself a most excellent time.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#for-full-effect

• 

  Roly Poly...

  Toddlers and babies. As seen here entertaining the masses.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#roly-poly

• 

  Tender

  A nano-second of gentle checking in from big bro, with his little sis.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#tender

• 

  C'mon

  You just died from cute, right?

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#cmon

• 

  Photo-Bomber

  Otherwise known as the Daddy. Every chance he'll get. This cute shot is of our little girl with her daycare provider whom we are very lucky to have. She is such a loving, quality friend to our babies. As are her children and her hubby. It was super cool to hang with them socially.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#photo-bomber

• 

  Pappa Love

  Going in for the kill. (His nose obviously).

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#pappa-love

• 

  Daddy's Little Girl

  Forever. Don't mess.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#daddys-little-girl

• 

  Daddy The Jungle-Gym

  Clearly, she's got him wrapped. And with good reason.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#daddy-the-jungle-gym

• 

  Oh, You Pretty (Little) Thing(s)

  David Bowie, I know you wrote that song for my girl. (Even though I really know it's all about the influences of occultist [Crowly], and Nietzsche [that famous philosopher] on us humans [and our obsolescence] in favour of the notion that aliens and teenagers should [and will] rule the world. Now ya know.)

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#oh-you-pretty-little-things

• 

  Perfect Score

  Just in case y'all were keeping score. Baby splits deserve a round of applause.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#perfect-score

• 

  Saucin'...

  It's what she does, yo. And ever well.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#saucin

• 

  Ima Gonna OWN You Cake!

  That's what this look says.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#ima-gonna-own-you-cake

• 

  From a Distance

  Watching the foreign proceedings with intent. The theory that babies don't know much? I beg to differ. She clearly knew something amazing was about to happen and acted with baited breath at such. Because babies are genius and they know things. Mostly amazing things.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#from-a-distance

• 

  Cutting Time

  Divvying up a 4 tier cake? Not for the faint of heart.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#cutting-time

• 

  All Good Things Come To Those Who Wait

  Like strawberry shortcake and so forth.

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#all-good-things-come-to-those-who-wait

• 

  Like a boss.

  A cake boss to be precise. Happy Day-We-Could-All- Get-Together-To-Celebrate-Your-Birthday, My Girl! (It's a cupcake for you on Thursday.)

  /babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/#like-a-boss

I?d like to extend a HUGE thank-you to our friends Cindy and Arvin Valenciano. Arv took all the fantastic pictures you just had the pleasure of viewing (and then some). Cindy is our daycare provider. She?s the bees knees!

More From Selena

18 Amazing Babywearing Images
12 Amazing DIY Baby Toy Tutorials
The Top 4 Reasons Moms Stop Breastfeeding?

You can also find me over yonder?

Via my humble?beginnings, mastering in general mayhem:?le petit r?ve
Of guilty pleasures, geekery and badassery: on the?Twitters
Connect to my hand-made personna on:?Facebook
Join me in my?Pinterest?or?Instagram?addictions

Source: http://blogs.babble.com/babys-first-year-blog/2012/07/24/24-of-the-most-adorable-1st-birthday-party-pics-really/

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New probe provides vital assist in brain cancer surgery

ScienceDaily (July 24, 2012) ? Performing surgery to remove a brain tumor requires surgeons to walk a very fine line. If they leave tumor tissue behind, the tumor is likely to regrow; if they cut out too much normal tissue, they could cause permanent brain damage.

"Primary brain tumors look just like brain tissue," says Keith Paulsen, PhD, a professor of biomedical engineering at Thayer School of Engineering and a member of the Cancer Imaging and Radiobiology Research Program at Norris Cotton Cancer Center. "But if you look at them under a particular kind of light, they look much different."

To improve their ability to differentiate between tumor cells and healthy tissue, surgeons can have patients take an oral dose of the chemical 5-aminolevulinic acid (ALA). An enzyme metabolizes ALA, producing the fluorescent protein protoporphyrin IX (PpIX). Tumor cells have a higher metabolic rate than normal cells, so they accumulate more PpIX -- and therefore fluoresce, or "glow," when exposed to blue light.

A cancer "flashlight"

But this method was thought to be not sensitive enough to highlight brain tumors that are less metabolically active, like low-grade gliomas. To address this problem, MD-PhD student Pablo Valdes, PhD, and his research mentors -- David Roberts, MD, the chief of neurosurgery at Dartmouth-Hitchcock Medical Center, and Dr. Paulsen -- used a probe (which they helped develop) that combines violet-blue and white light to simultaneously analyze both the concentration of PpIX and four other tumor biomarkers: PpIX breakdown products, oxygen saturation, hemoglobin concentration, and irregularity of cell shape and size. The probe reads how light travels when it hits the tissue, sends this data to a computer, runs it through an algorithm, and produces a straightforward answer as to whether the tissue is cancerous.

"Our big discovery is that we can use the probe's reading of the fluorescing agent to measure the existence of a low-grade tumor in tissue," says Dr. Paulsen. "The probe is basically an enabling technology to show that information to the surgeon -- a visual aid."

He says that when they first saw the results of using their fluorescing agent and probe on low-grade brain tumors, it was "jaw-dropping. The tumor glowed like lava."

The Thayer/Norris Cotton Cancer Center/Dartmouth-Hitchcock Medical Center team, which has been working on the brain probe for about six years, built on research that was originally conducted in Germany about 15 years ago. But the German research did not focus on low-grade tumors. The assumption, Dr. Paulsen says, was that, due to the blood-brain barrier, low-grade tumors did not have enough PplX and therefore would not fluoresce.

In a pilot study, Roberts operated on 10 patients with gliomas. He used a microscope throughout the surgery to see the fluorescence and used the hand-held probe to evaluate sections of the tissue where the fluorescence was not definitive. After the surgeries were complete, a pathologist evaluated how accurately the probe had identified tumor tissue.

Striking results

The results, published in the Journal of Biomedical Optics, are striking. Diagnoses based on only fluorescence had an accuracy of 64 percent. But when Roberts used the probe as well, the accuracy increased to 94 percent, meaning that Roberts was much more successful in differentiating between tumor tissue and normal tissue. Although the study was small, it introduces a promising method to help surgeons remove only what they want and nothing more.

Dr. Paulsen says that a protocol is in place for a similar study on lung cancer tumors. He thinks the brain probe may have applications for other cancers as well, but for now the research will have to proceed one cancer type at a time.

Portions of this article were written by Alannah Phelan and appeared in the Spring 2012 edition of Dartmouth Medicine.

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Source: http://www.sciencedaily.com/releases/2012/07/120724144536.htm

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Ion Torrent vies for $10 million genome prize

By Sharon Begley

NEW YORK | Tue Jul 24, 2012 10:08am EDT

NEW YORK (Reuters) - A genome-sequencing contest announced six years ago finally has its first entrant: Life Technologies Corp.'s Ion Torrent, which on Monday said it was entering the fray.

The Archon Genomics X Prize will award $10 million to the first team that sequences the complete genomes of 100 people aged 100 or older in 30 days or less, for no more than $1,000 each, and with an error rate of no more than 0.0001 percent.

No one else has been game since the contest was announced in 2006, when it would have taken 33 years and $100 million to do 100 genomes, estimates Ion Torrent founder and CEO Dr. Jonathan Rothberg. In January, the company said its Ion Proton Sequencer was ready to sequence a complete human genome in a day at a cost of $1,000.

"I can think of two reasons why companies have not signed up," said geneticist Craig Venter, who led the private sector effort to sequence the complete human genome, finishing in a dead heat with a government-backed project in 2000. He serves as a trustee of the foundation that created the prize.

"One is that $10 million isn't a significant sum to them. But when I look at their stock price I see that's actually a good fraction of their market capitalization," he said of companies like Life Technologies and Illumina. "The other reason is that, despite what their ads say, their technology doesn't measure up. I regard the X Prize as truth serum."

No other genome-sequencing companies contacted by Reuters said they intended to compete for the centenarian X Prize. Besides the cash and bragging rights, the company that sequences the genomes of 100 centenarians could stumble on some fascinating science and new leads in drug discovery.

"Illumina does not plan to participate," said a spokeswoman for the company, which fought off a takeover attempt by Roche Holding AG earlier this year. In January, Illumina announced that its next-generation sequencer, HiSeq 2500, will be able to sequence a human genome in about a day.

"We haven't entered so far and haven't announced any intention to do so for the time being," said a spokeswoman for privately held Oxford Nanopore Technologies Ltd., which caused a stir at a technology conference in February when it unveiled a device the size of a USB memory stick capable of sequencing 150 megabases of DNA per hour. The human genome has 6 billion bases, or chemical "letters" that spell out genes.

"We're waiting to learn more before deciding whether to join," said Dr. Clifford Reid, president and CEO of Complete Genomics Inc., which provides whole-genome sequencing services. Reid wants assurances that there will be "a level playing field and an unbiased measure of accuracy" so error rates are calculated in a way that's fair to each competitor.

That leaves Ion Torrent.

"All the numbers work," said Rothberg. "We'll have eight Protons (sequencers) running at a dedicated facility with about a dozen people, and we'll be able to sequence up to 100 billion bases every two hours."

That raw data must be assembled into their order on the 23 human chromosomes, a task analogous to putting the pages of the New York City phone book into the right sequence. The assembly process will take Ion Torrent most of the 30 days it has under X Prize rules.

HIGH-STAKES SCIENCE

The Archon prize is administered by the nonprofit X Prize Foundation, which was founded in 1995 to create and run high-stakes scientific competitions. Its name refers to Archon Minerals Ltd., a Canadian mining company whose president, Stewart Blusson, and his wife, Marilyn, funded the prize.

Express Scripts Holding Co., a pharmacy benefits manager, provides financial support for the prize's operations, which include developing an "answer sheet" (the correct genome sequences of the centenarians), said the foundation's Grant Campany.

Other companies have until May 31, 2013 to enter the ring. The countdown will start on September 5, 2013, when a judge from the foundation will deliver vials containing the DNA of 100 centenarians to each sequencing team. Each will have until October 4 to determine the 100 genome sequences, with the winner determined by accuracy.

While many studies that identify gene variants uncover those that increase the risk of disease, sequencing centenarians' genomes "will tell you about alleles (gene variants) that don't cause disease," said Rothberg. "These people don't have cancer, they don't have Alzheimer's disease, they don't have hypertension, they don't have heart disease."

That could yield promising new targets for drug development, with the aim of replicating the action of gene variants that protect the body against all kinds of ailments.

In fact, centenarians - who make up 0.2 percent of the U.S. population, or about 53,000 people - don't have a notably healthy lifestyle.

A 2011 study of 477 people aged 95 and older found that they are just as likely as the general population to have been overweight at any point in their life, to have smoked and drunk alcohol, and to have eaten a high-fat diet.

"Our centenarians - including one 107-year-old who runs a hedge fund - were no more likely to have followed healthy practices," said Dr. Nir Barzilai of Albert Einstein College of Medicine in New York City, who proposed the centenarian-genome contest to the X Prize Foundation.

Barzilai and colleagues also found centenarians are as likely as everyone else to have genes associated with cardiovascular disease and other life-shortening illnesses. But like their "unhealthy" lifestyle, their "disease genes" don't seem to hurt them.

That suggests what Barzilai calls a ??buffering'' mechanism in which "longevity genes might counter the disease genes and the unhealthy lifestyle."

Anyone born before September 5, 1913, can volunteer their DNA through the X Prize's website.

(Reporting by Sharon Begley; Editing by Michele Gershberg and M.D. Golan)

(This story corrects sequencing speed to 150 megabases of DNA per hour, from 150,000 DNA bases per hour in 8th paragraph)

Source: http://feeds.reuters.com/~r/reuters/scienceNews/~3/VolUrwozr7s/us-science-genome-prize-idUSBRE86M02G20120724

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The iRobot Doc Will See You Now: Roomba Maker Enters the ER

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Source: http://news.yahoo.com/irobot-doc-see-now-roomba-maker-enters-er-000222552.html

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